New Year's Eve, 1968: While driving on the Pearblossom Highway, a lesbian couple encounters the creator of the universe. Laid to rest for 40 years, the women wake up on New Year's Day as reborn creatures.

Driven by a history of dating pitfalls and frustration with men, Alexis and her best friend Lindsay decide to turn the tables and devise a plan to lure unsuspecting men close enough to knock them out and drag them back to their lair for their own satisfaction. When an absent father and an obsessive ex-boyfriend force Alexis to confront her issues with men, the girls' plan goes awry and Alexis falls head over heels in love with one of her male conquests. Lindsay, consumed by her darker nature, decides to go out on the hunt alone, leading to her arrest. In the end, the girls reunite and recognize the strength of their friendship and that ultimately; their own self worth determines how men will treat them.

Julia Jones is unhappy. She's overweight, spends forever working at her fathers diner, and believes she will always be lonely. This is until she meets Grant Fockyerdoder. Before they can have their dream wedding, they must meet each others parents and survive the scheming Andy.

The storyline revolves around three thirtysomething friends who break the monotony of their uninspired lives by vacationing on an island that's a popular spring break getaway for college co-eds. One of the women works for a powerful senator whose daughter is one of those co-eds, only she's as geeky as her chaperones.